| Autor: |
Sarandol, Emre, Erdinc, Selda, Senol, Emel, Ersoy, Alparslan, Surmen-Gur, Esma |
| Zdroj: |
Nefrología (English Edition); 20220101, Issue: Preprints |
| Abstrakt: |
Oxidative stress increases oxidizability of apolipoprotein-B containing lipoproteins and decreases paraoxonase (PON) activity in hemodialysis (HD) patients and plays an important part in the development of atherosclerotic cardiovascular diseases. In HD patients, plasma ascorbic acid (AA) levels are decreased either due to the loss by hemodialysis membranes or due to malnutrition and contribute to the imbalance of antioxidant defense mechanisms. We hypothesized that long-term ascorbic acid (AA) supplementation recovers oxidizability of lipoproteins in HD patients by reinforcing PON activity. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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