Inhibitory activity of 3-methylenhydroxy-5-methoxy-2,4-dihydroxy tetrahydrofurane isolated from Selaginella lepidophylaon smooth muscle of Wistar rat

Autor: G., Salud Pérez, Pérez G., Rosa M., Pérez G., Cuauhtémoc, Zavala S., Miguel A., Vargas S., Rosario
Zdroj: Pharmaceutica Acta Helvetiae; December 1994, Vol. 69 Issue: 3 p149-152, 4p
Abstrakt: A new compound, 3-methylenhydroxy-5-methoxy-2,4-dihydroxy tetrahydrofurane, has been isolated from a methanol extract of Selaginella lepidophyla. The structure is based on 1H-NMR, 13C-NMR and MS analysis. The compound was tested on uterus (oestrus), ileum and duodenum of Wistar rats. It proved to have a slight inhibitory effect on the contraction response of the uterus, but it did not have any effect on the two other muscles.
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