| Autor: |
Wang, Fei, Zhu, Fuying, Ren, Enxiang, Zhang, Qiang, Lu, Guo-Ping, Lin, Yamei |
| Zdroj: |
Catalysis Science & Technology; 2022, Vol. 12 Issue: 23 p7018-7026, 9p |
| Abstrakt: |
The development of efficient and green synthetic strategies for N-heterocycle synthesis has always been a research hotspot in organic synthesis. A facile one-pot iron-catalyzed synthesis of quinazolines from alcohols in water has been disclosed for the first time, in which a N-doped carbon encapsulated Fe–FeOxmaterial (Fe–FeOx@NC) is applied as a catalyst, and various quinazolines (25 examples, 62–99%) are synthesized. The iron nanoparticles wrapped by nitrogen-doped carbon layers in Fe–FeOx@NC with strong anti-poisoning ability is the main reason for the high performance in the reaction. This protocol offers several advantages including the use of air as an oxidant, water as a solvent, and recyclable iron as a catalyst and high atom and step economy. |
| Databáze: |
Supplemental Index |
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