| Autor: |
Kostić, Marina, Ivanov, Marija, Markovic, Tatjana, Sanković Babić, Snežana, Barros, Lillian, Calhelha, Ricardo, Sokovic, Marina, Ciric, Ana |
| Zdroj: |
Journal of Essential Oil Research; November 2022, Vol. 34 Issue: 6 p533-543, 11p |
| Abstrakt: |
ABSTRACTThe chemical composition and biological activity of essential oils (EOs) from leaves of Origanum minutiflorumO. Schwarz & P.H.Davis, and seeds of Coriandrum sativumL. were investigated. Chemical analyses of EOs were performed and the major components were carvacrol (81.5%) and linalool (69.6%), respectively. The antimicrobial activity was assessed against several bacteria originating from the tonsillar tissue. Activities of EOs against Staphylococcus aureusbiofilm were investigated, as well as the effect of the mixture of these EOs and antibiotics against the pathogen. The antioxidant activity of both EOs was determined by TBARS assay, and examined wild oregano EO showed better activity. Also, cytotoxicity of EOs was evaluated in vitroand both EOs showed potential to inhibit further proliferation of tumor cells. This study reported for the first time the effects of EOs on chronic tonsillitis causative pathogens, supporting their role as a natural bioactive therapeutic agent with possible antimicrobial applications. |
| Databáze: |
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