Switching under selection: how CoREST controls endocrine therapy resistance in ER+breast cancer
| Autor: | Chick, Brent Y., Hargreaves, Diana C. |
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| Zdroj: | Nature Structural and Molecular Biology; 20220101, Issue: Preprints p1-3, 3p |
| Abstrakt: | New research shows that the CoREST complex controls the acquisition of endocrine therapy resistance in estrogen receptor-positive breast cancers. Profiling data show that this resistance transition is accompanied by a functional retargeting of CoREST on chromatin in coordination with cJUN and SWI/SNF (cBAF). |
| Databáze: | Supplemental Index |
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