| Autor: |
Costa, Edja Maria Melo de Brito, Maia, Carolina Medeiros de Almeida, Vasconcelos, Priscilla Guimarães Silva, Portela, Maristela Barbosa, Barboza, Caroliny Mello, Cardoso, Abel Silveira, de Araújo Soares, Rosangela Maria, dos Santos, André Luis Souza |
| Zdroj: |
Brazilian Journal of Microbiology; December 2022, Vol. 53 Issue: 4 p1969-1977, 9p |
| Abstrakt: |
The present study aimed to compare the oral Candidarate between infected and uninfected children with the human immunodeficiency virus (HIV), as well as analyze the association between Candidaspp. and predisposing factors of colonization, like oral biofilm index, caries experience, and laboratory markers of AIDS progression. A cross-sectional study was employed. Candidaspecies were identified and quantified from saliva samples of 50 HIV-infected and 50 uninfected children. Biofilm index and decayed, missing, and filled teeth (dmft/DMFT) indices were assessed by oral clinical examinations. Additionally, CD4+T lymphocyte count and viral load were obtained from medical records of the HIV-infected children. Candidaspecies were cultured from 74% of the HIV-infected children and 46% of uninfected ones (p= 0.0076). Candida albicansand Candida parapsilosiswere the most frequently isolated species in both studied groups. The isolation of Candidaspecies was significantly higher in HIV-infected children with CD4 ≤ 15% (p= 0.0146); it had influence of mature oral biofilm and the caries index (dmft + DMFT ≥ 8) (p< 0.05) and was associated with the plasma viral load. The present data show that the HIV infection, oral biofilm index, caries experience, and laboratory markers of AIDS progression exert an influence on the prevalence of oral Candidain children. |
| Databáze: |
Supplemental Index |
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