| Autor: |
Rzayev, Javid, Zhang, Zhuan, Durand, Natacha, Soulé, Jean-François |
| Zdroj: |
Organic Letters; 20220101, Issue: Preprints |
| Abstrakt: |
We report an Rh(I)-catalyzed C–H bond alkylation of PhenCarPhos [N-(2-(diphenylphosphaneyl)phenyl)carbazole] and some congener phosphine ligands with alkenes. The C–H bond functionalization occurred exclusively at the C1 position of the carbazolyl unit because the trivalent phosphine acts as a directing group. This protocol provides straightforward access to a large library of C1-alkyl substituted PhenCarPhos, which outperformed common commercial or unfunctionalized phosphines and their precursors in the Pd-catalyzed carbon dioxide-fixation reactions with propargylic amines. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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