| Autor: |
Cheng, Yi-nan, Sun, Liansheng, Meng, Haoguang, Jiang, Zhenhua, Zhang, zhijia, Yun, Yuanyuan, Wang, Xiafei, Yan, Jingming, Yang, Xifa, Zhou, Haifeng, Li, Honglian |
| Zdroj: |
Journal of Agricultural and Food Chemistry; August 2022, Vol. 70 Issue: 33 p10305-10315, 11p |
| Abstrakt: |
Wheat root diseases can seriously reduce yields and quality of wheat. 1,2,4-Triazole benzoyl arylamine derivatives previously showed good activities against some wheat root fungal pathogens. To further systematically disclose the structure–activity relationship, a series of benzoyl arylamines were designed and prepared. Their structures were characterized and fungicidal activities against Gaeumannomyces graminisvar. triticiand Fusarium graminearumwere evaluated. The results indicated that the structure of the N-heterocyclic group and the substituted group and their position on the benzamide scaffold had an important influence on the activities, as predicted. Finally, compound 18fwas found to show excellent activities against G. graminisvar. tritici, F. graminearum, Fusarium culmorum, Fusarium pseudograminearum, and Fusarium moniliformewith half-maximum effective concentrations of 0.002, 0.093, 0.011, 0.881, and 0.287 μg/mL, respectively. These results proposed that compound 18fdeserved serious consideration as a novel fungicide candidate for the control of wheat root diseases. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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