| Autor: |
Viturro, C. I., Fuente, J. R. de la, Maier, M. S. |
| Zdroj: |
Journal of Natural Products; May 2004, Vol. 67 Issue: 5 p778-782, 5p |
| Abstrakt: |
In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A−D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana. |
| Databáze: |
Supplemental Index |
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