| Autor: |
Meruelo, D, Kornreich, R, Rossomando, A, Pampeno, C, Boral, A, Silver, J L, Buxbaum, J, Weiss, E H, Devlin, J J, Mellor, A L |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; June 1986, Vol. 83 Issue: 12 p4504-4508, 5p |
| Abstrakt: |
Transformation of murine thymocytes by radiation leukemia virus is associated with reduced expression of the class I antigens encoded in the major histocompatibility complex (MHC) and increased methylation and altered restriction enzyme patterns of MHC DNA. These changes may play a role in host susceptibility to virus-induced leukemogenesis and accord with the notion that viral genomes play a regulatory function when they integrate adjacent to histocompatibility genes. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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