| Autor: |
Hagenbüchle, O, Schibler, U |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; April 1981, Vol. 78 Issue: 4 p2283-2286, 4p |
| Abstrakt: |
Initiation of transcription on major late DNA of adenovirus serotype 2 and the beta-globin gene of the mouse was studied by using ribonucleoside [beta-32P]triphosphates as labeled precursors in vitro. The 5' termini of discrete runoff transcripts of both templates were preferentially labeled. The beta phosphate of the cap structure was labeled by [beta-32P]ATP but not [beta-32P]GTP, indicating that the beta phosphate of the cap is contributed by the initiating nucleoside triphosphate (ATP in both cases). Therefore, capping occurs on the initial nucleotide of these transcripts. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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