| Autor: |
Scarborough, R M, Jamieson, G C, Kalish, F, Kramer, S J, McEnroe, G A, Miller, C A, Schooley, D A |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; September 1984, Vol. 81 Issue: 17 p5575-5579, 5p |
| Abstrakt: |
Two cardioacceleratory peptides from the corpora cardiaca of Periplaneta americana have been purified by gel filtration and reversed-phase liquid chromatography, Based on analysis of the intact factors and their chymotryptic fragments, we have assigned the primary structure of these octapeptides as pGlu-Val-Asn-Phe-Ser-Pro-Asn-Trp-NH2, designated periplanetin CC-1, and pGlu-Leu-Thr-Phe-Thr-Pro-Asn-Trp-NH2, designated periplanetin CC-2. They represent new members of a family of invertebrate peptides that includes locust adipokinetic hormone and crustacean red-pigment concentrating hormone. Both peptides show adipokinetic activity in grasshoppers and hyperglycemic activity in cockroaches. One of these peptides (CC-2) has provocative sequence homology with the NH2-terminal portion of glucagon. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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