| Autor: |
Roberts, J W, Grula, J W, Posakony, J W, Hudspeth, R, Davidson, E H, Britten, R J |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; August 1983, Vol. 80 Issue: 15 p4614-4618, 5p |
| Abstrakt: |
Clones of full-length mtDNA have been isolated from a Strongylocentrotus franciscanus recombinant DNA library by screening a cDNA clone of cytochrome oxidase subunit 1 mRNA. Restriction fragment cross-hybridization analysis shows the following difference in gene arrangement between sea urchin and human mtDNA. The 16S rRNA and cytochrome oxidase subunit 1 genes are directly adjacent in sea urchin mtDNA. These two genes are separated in human and other mammalian mtDNAs by the region containing unidentified reading frames 1 and 2. In spite of the difference in gene order, gene polarity appears to have been conserved. We conclude that the difference in gene order reflects a rearrangement that took place in the sea urchin lineage since sea urchins and mammals last shared a common ancestor. |
| Databáze: |
Supplemental Index |
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