Autor: |
Skopek, T R, Liber, H L, Kaden, D A, Thilly, W G |
Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; September 1978, Vol. 75 Issue: 9 p4465-4469, 5p |
Abstrakt: |
Forward mutation to 8-azaguanine resistance and reverse mutation to histidine prototrophy were measured in Salmonella typhimurium after treatment with 16 mutagens of both base-substitution and frameshift classes. The two approaches were found to be equisensitive for all 16 mutagens--i.e., induction of significant mutation occurred at similar concentrations in the forward mutation assay and in the most sensitive of the five Ames tester strains. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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