Autor: |
Bingham, P M, Baltz, R H, Ripley, L S, Drake, J W |
Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; November 1976, Vol. 73 Issue: 11 p4159-4163, 5p |
Abstrakt: |
Heat induces transversions (as well as transitions) at G-C base pairs in bacteriophage T4. The target base for transversions is guanine,which is converted to a product which is sometimes replicated and transcribed as a pyrimidine.A model for this process is proposed in which the deoxyguanosine glycosidic bond migrates from N9 to N2: the resulting deoxyneoguanosine may pair with normal guanine to produce G-C leads to C-G transversions. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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