| Autor: |
Hadden, J W, Hadden, E M, Sadlik, J R, Coffey, R G |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; May 1976, Vol. 73 Issue: 5 p1717-1721, 5p |
| Abstrakt: |
To better define cell surface-related changes involved in lymphocyte activation, we studied native concanavalin A (Con A) and succinylated concanavalin A (Suc-Con A) for their effects on proliferation and cyclic nucleotide levels of human peripheral blood lymphocytes. At optimal mitogenic concentrations, the two forms of Con A induce equivalent proliferation; however, the mitogenic activity of Con A progressively decreases above 50 mug/ml. In contrast, the mitogenic activity of Suc-Con A is not decreased even at 250 mug/ml. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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