| Autor: |
Momany, F A, Aguanno, J J, Larrabee, A R |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; September 1976, Vol. 73 Issue: 9 p3093-3097, 5p |
| Abstrakt: |
A parameter is developed which relates the amino acid composition and subunit size of a protein to the degradative rate in vivo. This parameter was calculated for 11 rat liver proteins and a plot versus the half-lives of these proteins is linear and has a coefficient of correlation of -0.96. Evidence is presented which suggests that the density of excess acidic amino acids on the surface of the protein is the most important factor in determining differential turnover. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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