| Autor: |
Lisman, J E, Goldring, M A |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America; July 1988, Vol. 85 Issue: 14 p5320-5324, 5p |
| Abstrakt: |
The feasibility of long-term information storage by brain type II Ca2+/calmodulin-dependent protein kinase molecules is explored. Recent evidence indicates that this protein has switch-like properties. Equations are derived showing that a single kinase holoenzyme could form a bistable switch having the stability necessary to encode long-term memory, and that a group of kinase molecules, such as that contained within the postsynaptic density, could form a device capable of storing graded information. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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