Autor: |
Huang, Yao, Geng, Hongchao, Wu, Zeming, Sun, Leilei, Ji, Chenhui, Grimes, Craig A., Feng, Xinxin, Cai, Qingyun |
Zdroj: |
Biomaterials Science; 2022, Vol. 10 Issue: 14 p3972-3980, 9p |
Abstrakt: |
Bacterial diseases pose a serious threat to human health. Continued development of precise diagnostic methods and synergistic therapy techniques for combating bacteria are needed. Herein a hybrid nanosystem (Ag2S@ZIF-Van NS) was constructed by one-step self-assembly of Zn2+, vancomycin (Van) and Ag2S quantum dots (QDs). The nanosystem possesses excellent second near-infrared transparency window (NIR-II) fluorescence properties (∼1200 nm emission wavelength), good photothermal conversion properties, and biocompatibility. The material system enables precise, targeted NIR-II fluorescent imaging of bacterial inflammation in vivoas well as promoting anti-bacterial and wound healing effects. |
Databáze: |
Supplemental Index |
Externí odkaz: |
|