| Autor: |
Ishida, Yamato, Tasaki, Koshi, Katoh, Yohei, Nakayama, Kazuhisa |
| Zdroj: |
Molecular Biology of the Cell; August 2022, Vol. 33 Issue: 9 |
| Abstrakt: |
Mutations of IFT52, a subunit of the IFT-B complex, cause skeletal ciliopathies. IFT52 variants found in ciliopathy individuals are compromised in terms of IFT-B complex formation from two subcomplexes and its interaction with kinesin-II. IFT52-KO cells expressing IFT52 variants showed mild ciliogenesis defects and a decrease in ciliary IFT-B level. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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