Fusion plasmid carrying the colistin resistance gene mcrof Escherichia coliisolated from healthy residents

Autor: Hoang, Hoa Thi Thanh, Higashi, Ayano, Yamaguchi, Takahiro, Kawahara, Ryuji, Calvopina, Manuel, Bastidas-Caldés, Andres, Yamamoto, Mayumi, Yamamoto, Yoshimasa
Zdroj: Journal of Global Antimicrobial Resistance; September 2022, Vol. 30 Issue: 1 p152-154, 3p
Abstrakt: The extensive spread of colistin resistance represents an enormous concern to infectious disease treatment, because colistin is one of the few effective antibiotics against multidrug-resistant bacterial infections, including carbapenem-resistant bacteria. This dissemination can be caused by plasmid transfer containing the colistin resistance gene mcr. Therefore, the plasmid host range affects horizontal gene transfer. This study reports a fusion plasmid of different incompatibility types, which could easily expand the plasmid host range, allowing widespread mcrprevalence in the microbial community.
Databáze: Supplemental Index