Autoradiographic and biochemical studies of drug distribution in the liver III. [14C] Aminotriazole

Autor: Fujii, Toshihiko, Miyazaki, Hisashi, Hashimoto, Masahisa
Zdroj: European Journal of Drug Metabolism and Pharmacokinetics; July 1984, Vol. 9 Issue: 3 p257-265, 9p
Abstrakt: Whole body autoradiography revealed that the distribution pattern of [14C]aminotriazole in the mouse liver was homogeneous after intravenous administration of the labeled agent and then became heterogeneous (or reticular). Microautoradiography by dry-moun-ting method revealed that the macroscopic heterogeneous pattern was due to the central localization of the radioactive compound in the hepatic lobule.
Databáze: Supplemental Index