Understanding the effects of Abhraka Bhasmaon genotoxicity and its DNA Repair potential in mouse model

Autor: Kulala, Divya S., Prasad, Keshava, Reddy, Poojitha S., M, Swathi, Joshi, Manjunath B., Satyamoorthy, K., Parashiva, Guruprasad K.
Zdroj: Journal of Ayurveda and Integrative Medicine; 20220101, Issue: Preprints
Abstrakt: Metal toxicity is of major concern to human health. The metals may modulate molecular mechanisms of various pathways. Rasashastra, the branch of Ayurveda, narrates the properties, unique preparation, processing techniques, and therapeutic uses of minerals. The use of herbal metallic preparations has evoked concern for their potential to produce toxicity, interest in efficacy as therapeutic agents and safety related issues. Abhraka Bhasma, is one such incinerated herbo-metallic preparation of mica, widely used by traditional medicine practitioners. Although there are reports of Abhraka Bhasmaon beneficial effects, clear evidence is lacking on the effect of Abhraka Bhasmaon genetic toxicity and DNA repair.
Databáze: Supplemental Index