Autor: |
Alzu'bi, Hossam, Al-abdouh, Ahmad, Haq, Ikram-Ul, AbuRmilah, Anan, Deshmukh, Abhishek |
Zdroj: |
Circulation (Ovid); November 2021, Vol. 144 Issue: Supplement 1 pA13998-A13998, 1p |
Abstrakt: |
Background:Many cardiac implantable devices have the capability of monitoring the volume status in patients with heart failure by tracking the intra-thoracic impedance changes over time measured by OptiVol fluid index.Objective:The aim of this study is to evaluate the association between the intra-thoracic impedance measured by OptiVol fluid index and the onset of tachyarrhythmias.Methods:We searched Medline and EMBASE databases through January 2021 looking for studies evaluating intra-thoracic impedance measured by OptiVol with either ventricular tachycardia/ventricular fibrillation (VT/VF) or atrial tachycardia/atrial fibrillation (AT/AF). After extracting the data from each study, we calculated the odds ratio with 95% confidence intervals using RevMan 5 software.Results:Ten studies met our inclusion criteria with a total of 118,504 patients were included in our analysis. Seven studies measured VT/VF included 94,816 patients and 5 studies measured AT/AF included 23,688 patients. Two studies measured both AT/AF and VT/VF. The odds ratio for developing VT/VF with OptiVol fluid index crossing a threshold of 60 Ω-days was 1.55 (95% CI 1.35, 1.78) (P<0.00001) and for developing AT/AF was 1.79 (95% CI 1.43, 2.24) (P<0.00001) {Figure1}Conclusion:The decrease in intra-thoracic impedance measured by OptiVol fluid index threshold crossing of 60 Ω-days is associated with higher risk for developing new onset AT/AF and VT/VF.Key Words:intra-thoracic impedance; OptiVol; tachyarrhythmiaFigure1:Forest Plot for risk of developing VT/VFFigure:Forest Plot for risk of developing AT/AF |
Databáze: |
Supplemental Index |
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