ACE gene dosage determines additional autonomic dysfunction and increases renal angiotensin II levels in diabetic mice

Autor: Moraes, Oscar Albuquerque de, Flues, Karin, Scapini, Kátia Bilhar, Mostarda, Cristiano, Evangelista, Fabiana de Sant'Anna, Rodrigues, Bruno, Dartora, Daniela Ravizzoni, Fiorino, Patricia, Angelis, Kátia De, Irigoyen, Maria Cláudia
Zdroj: Clinics; January 2018, Vol. 73 Issue: 1
Abstrakt: The present study aimed to investigate cardiovascular autonomicmodulation and angiotensin II (Ang II) activity in diabetic mice that were genetically engineered to harbor two or three copies of the angiotensin-converting enzyme gene.
Databáze: Supplemental Index