| Autor: |
Marrero, J., Rodriguez, A. D., Baran, P., Raptis, R. G., Sanchez, J. A., Ortega-Barria, E., Capson, T. L. |
| Zdroj: |
Organic Letters; May 2004, Vol. 6 Issue: 10 p1661-1664, 4p |
| Abstrakt: |
Bielschowskysin is a naturally occurring diterpene isolated from the Caribbean gorgonian octocoral Pseudopterogorgia kallos. Its highly oxygenated hexacyclic structure is based on a previously undescribed tricyclo[9.3.0.02,10]tetradecane ring system that was established through spectroscopic analysis and X-ray crystallographic analysis. Bielschowskysin was shown to exhibit antimalarial activity against Plasmodium falciparum as well as strong anticancer activity against two human cancer cell lines. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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