Drug resistance in leprosy: An update following 70years of chemotherapy

Autor: Aubry, A., Sammarco Rosa, P., Chauffour, A., Fletcher, M.L., Cambau, E., Avanzi, C.
Zdroj: Infectious Diseases Now; August 2022, Vol. 52 Issue: 5 p243-251, 9p
Abstrakt: •Antimicrobial resistance is found in Mycobacterium leprae, causative agent of leprosy.•History of chemotherapy can explain the current rate of drug resistance.•Molecular methods are the standard methods to detect drug resistance in leprosy.•Signs of positive selection in new genes are reported.•New drugs are under investigation to overcome resistance.
Databáze: Supplemental Index