| Autor: |
Mariotti, Angelo, Monroe, Philip J. |
| Zdroj: |
Dental Clinics of North America; April 1998, Vol. 42 Issue: 2 p245-262, 18p |
| Abstrakt: |
Since the establishment of bacteria-laden plaque as a causative agent in gingivitis,34the search for specific bacteria that induce different types of periodontitis has generated extensive research. In contrast to many other microbial-induced disorders, the specific periodontal pathogen(s) has not been identified to date. Therefore, the search for an effective systemic agent to prevent the loss of attachment through the selective reduction of known periodontal pathogens has remained elusive. It is not surprising then that antibiotics are not used solely to manage periodontal diseases but rather as an adjunct to the mechanical débridement of root surfaces in select periodontal diseases. Further, the sole use of antibiotics in patients with adult periodontitis (or those who exhibit signs of inflammation but are periodontally stable) has shown little benefit and only increases the chance of microbial resistance to antibiotics. Despite these limitations, considerable progress in antibiotic therapy has delivered regimens that enhance the effectiveness of conventional therapy. |
| Databáze: |
Supplemental Index |
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