| Autor: |
Boily-Daoust, Catherine, Fortin, Marc, Dumas, Alain, Bussières, Jean |
| Zdroj: |
Canadian Journal of Respiratory, Critical Care, and Sleep Medicine; March 2022, Vol. 6 Issue: 2 p73-75, 3p |
| Abstrakt: |
AbstractBoth whole lung lavage (WLL) and inhaled granulocyte macrophage colony-stimulating factor (GM-CSF) have been shown to improve patient outcomes in pulmonary alveolar proteinosis (PAP). We report a case of autoimmune PAP that was refractory to bilateral WLL, relapsing rapidly after each of her 6 treatments. A systemic GM-CSF trial was also ineffective. Her seventh WLL was followed immediately by inhaled GM-CSF, and the patient experienced a complete and sustained remission. Our case suggests that those 2 treatments might have a synergistic effect. |
| Databáze: |
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