Autor: |
Kuwar, Suyog S., Mishra, Ruchir, Banerjee, Rahul, Milligan, Jason, Rydel, Timothy, Du, Zijin, Xie, Zhidong, Ivashuta, Sergey, Kouadio, Jean-Louis, Meyer, Jason M., Bonning, Bryony C. |
Zdroj: |
Current Research in Insect Science; January 2022, Vol. 2 Issue: 1 |
Abstrakt: |
•Cry3Bb1 engineering for receptor retargeting to counter WCR resistance described•Phage display screens against BBMV or recombinant insecticidal-protein receptors•77 gut binding peptides selected and engineered into 284 new variants of Cry3Bb1•112 variants were active against susceptible but not resistant WCR•Engineering of Cry3Bb1 Domain II loops 1 and 2 disrupted insecticidal activity•Sites for Cry3Bb1 engineering and implications for Cry3Bb1 resistance discussed |
Databáze: |
Supplemental Index |
Externí odkaz: |
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