Impact of glutathione S transferases P1 (Ile105Val) variants on the risk of GSTp, phosphorylated c-Jun kinase, and P53 phenotypic expression and their implications on overall survival outcomes in non-small cell lung cancer patients treated with chemotherapy

Autor: Pathak, Anumesh K, Husain, Nuzhat, Shukla, Saumya, Pandey, Rahul Kumar, Kant, Surya, Bala, Lakshmi
Zdroj: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis; 20220101, Issue: Preprints
Abstrakt: This study focused on GST-M1, T1 null, and P1 Ile105Val variant genotypes associated with the risk of altered expression of GSTp, pJNK, and P53 in NSCLC patients. These markers and overall survival (OS) were correlatedwith a key set of clinicopathological characteristics.
Databáze: Supplemental Index