| Autor: |
Zhou, Yuan, Xiong, Tong, Zhou, Li-Yan, Li, Hong-Yan, Xiao, You-Cai, Chen, Fen-Er |
| Zdroj: |
Organic Letters; January 2022, Vol. 24 Issue: 2 p791-796, 6p |
| Abstrakt: |
The catalytic asymmetric synthesis of borylated 3-hydroxyoxindoles by addition of gem-diborylalkanes to isatins is disclosed. Chiral 3-hydroxyoxindoles bearing two contiguous stereogenic centers were produced in up to >20:1 dr and 99% ee. The synthetic utility of the corresponding products is presented through several transformations of the boryl moiety. This report provides an efficient strategy to incorporate a boryl functional group toward the synthesis of 3-hydroxyoxindoles. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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