Septoclasts expressing epidermal fatty acid-binding protein (E-FABP, FABP5) in endochondral ossification

Autor: Bando, Yasuhiko, Sakashita, Hide, Nagasaka, Arata, Sakiyama, Koji, Tokuda, Nobuko, Iseki, Shoichi, Owada, Yuji, Amano, Osamu
Zdroj: Journal of Oral Biosciences; 20210101, Issue: Preprints
Abstrakt: Long-chain fatty acids (LCFAs) and retinoic acid (RA) are abundant in the growth plates (GPs) of long bones; however, their roles have not been elucidated. We observed that epidermal fatty acid-binding protein (E-FABP/FABP5) with a high affinity for both LCFAs and RA is exclusively expressed in the septoclasts located at the chondro-osseous junction (COJ) of the GP.
Databáze: Supplemental Index