Both‐In‐One Hybrid Bacteria Suppress the Tumor Metastasis and Relapse via Tandem‐Amplifying Reactive Oxygen Species‐Immunity Responses (Adv. Healthcare Mater. 21/2021)

Autor: Sun, Mengchi, Ye, Hao, Shi, Qinghua, Xie, Jun, Yu, Xiang, Ling, Hao, You, Song, He, Zhonggui, Qin, Bin, Sun, Jin
Zdroj: Advanced Healthcare Materials; November 2021, Vol. 10 Issue: 21
Abstrakt: Synergistic Cancer Therapy In article number 2100950by Bin Qin, Jin Sun, and co‐workers, a both‐in‐one hybrid bacteria, wherein the chemotherapeutic drug doxorubicin is integrated onto the surface of glucose dehydrogenase‐overexpressed non‐pathogenic Escherichia colistrain, potentiates stimulated systemic antitumor immune responses, thereby significantly inhibiting tumor metastasis, postsurgical regrowth, and primary/distal tumor relapse in four different tumor models.
Databáze: Supplemental Index