| Autor: |
Patil, Arun Angelo, Simmons, Amelia, Nilles-Melchert, Thomas, Pandey, Deepak Kumar |
| Zdroj: |
The Egyptian Journal of Otolaryngology; December 2021, Vol. 37 Issue: 1 |
| Abstrakt: |
Background: Though surgery can correct nasal septal defects through a procedure called septoplasty, many people seek non-surgical options. Papain enzyme has been used in the past to lyse intervertebral disc and has shown to have a lytic effect on cartilage. Therefore, in this paper, the feasibility to use papain for septoplasty was studied. Results: The treated group showed significant lysis with the disintegration of the cartilage, both in the in vitro and cadaver study. Conclusion: This study shows that papain can lyse cartilage. It also shows that submucosal injection of papain around nasal cartilage will lyse the septal cartilage. Based on prior experience with papain for disc herniation and the present study, it is worthwhile to further investigate this procedure using live animals. |
| Databáze: |
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