| Autor: |
Oraebosi, Michael Ikechukwu, Olurishe, Temidayo Olutoyin, Anafi, Sherifat Bola, Bisalla, Mohammed |
| Zdroj: |
Annales Pharmaceutiques Françaises; 20210101, Issue: Preprints |
| Abstrakt: |
•Pathophysiology of diabetes mellitus involves reactive oxygen species-mediated oxidative stress•Blood glucose, oxidative stress and endogenous antioxidants in diabetes are expressed in rhythms•Hence therapy requires drug administration time to match these rhythms•Chronomodulated alpha-lipoic acid/nifedipine/glimepiride therapy mitigated neuropathy in rats•Circadian rhythm-based therapy in management of neuropathy may be of clinical benefit in man |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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