| Autor: |
Zhang, Hongdou, Xu, Jun, Ouyang, Yani, Yue, Xiaoguang, Zhou, Chenxin, Ni, Zhigang, Li, Wanmei |
| Zdroj: |
Chinese Chemical Letters; 20210101, Issue: Preprints |
| Abstrakt: |
Herein, an efficient molecular oxygen-mediated method for the selective hydroxyalkylation and alkylation of quinoxalin-2(1H)-ones with alkylboronic acids under transition-metal free conditions has been developed. This strategy demonstrates a broad scope of quinoxalin-2(1H)-ones and alkylboronic acids, giving 3-hydroxyalkylquinoxalin-2(1H)-ones and 3-alkylquinoxalin-2(1H)-ones in moderate-to-good yield. Control experiments reveal that a radical pathway is involved. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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