Fractal dimension in CT low attenuation areas is predictive of long-term oxygen therapy initiation in COPD patients: results from two observational cohort studies

Autor: Ibaraki, Takahiro, Tomoda, Koich, Fujioka, Nobuhiro, Sakaguchi, Kazuhiro, Fujita, Yukio, Yamamoto, Yoshifumi, Hontsu, Shigeto, Yamauchi, Motoo, Yoshikawa, Masanori, Tanabe, Naoya, Tanimura, Kazuya, Sato, Susumu, Saeki, Keigo, Muro, Shigeo
Zdroj: Respiratory Investigation; 20210101, Issue: Preprints
Abstrakt: Some chronic obstructive pulmonary disease (COPD) patients develop hypoxemia with disease progression, with some even requiring long-term oxygen therapy (LTOT). Lung function, especially diffusing capacity, and the annual decline in PaO2, are reported to be predictive factors of chronic respiratory failure. However, the association between lung morphometry evaluated using computed tomography (CT) images and LTOT initiation is unknown.
Databáze: Supplemental Index