| Autor: |
Hoffman, E K, Trusko, S P, Freeman, N, George, D L |
| Zdroj: |
Molecular and Cellular Biology; July 1987, Vol. 7 Issue: 7 p2592-2596, 5p |
| Abstrakt: |
We isolated and characterized the 5' region of the mouse c-Ki-ras gene, including a 5' untranslated exon (exon 0). These studies used genetic material from Y1 mouse adrenocortical tumor cells in which the c-Ki-ras gene is amplified and overexpressed. Our data demonstrate that transcription initiates at multiple sites, predicting size heterogeneity at the 5' ends of the c-Ki-ras mRNAs. Using transient expression assays, we identified a genomic fragment within the 5' region which exhibits bidirectional promoter activity. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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