Theta Particles: a Structure Found in Hamster Sarcoma Virus

Autor: Albino, Anthony P., deHarven, Etienne, Sanders, F. Kingsley
Zdroj: The Journal of Virology; September 1972, Vol. 10 Issue: 3 p477-483, 7p
Abstrakt: Hamster sarcoma virus (HaSV), a ribonucleic acid tumor virus, pelleted from tissue culture fluid manifests type C morphology by electron microscopy. However, if virus is first concentrated by polyethylene glycol or ammonium sulfate followed by density gradient banding, the virus shows a dramatically atypical barred core structure, termed “theta particles.” This structure suggests a condensation of the ribonucleoprotein into a flat disc. Atypical particles are found with HaSV and not in similarly treated feline leukemia virus or Rauscher-murine leukemia virus. Differences in the composition of HaSV as compared with these other viruses may be responsible for the production of such particles.
Databáze: Supplemental Index
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