| Autor: |
Gilman, M Z, Wilson, R N, Weinberg, R A |
| Zdroj: |
Molecular and Cellular Biology; December 1986, Vol. 6 Issue: 12 p4305-4316, 12p |
| Abstrakt: |
We tested sequences flanking the mouse c-fos gene for the ability to form specific DNA-protein complexes with factors present in crude nuclear extracts prepared from mammalian cells. Three such complexes were detected. One complex formed in a region necessary for the induction of c-fos expression by serum growth factors. Two additional complexes formed at sequences that contribute to basal c-fos promoter activity in vivo. These complexes represent three novel sequence-specific DNA-binding activities which appear to participate in the regulation of c-fos transcription. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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