Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system
| Autor: | Lebkowski, J S, Miller, J H, Calos, M P |
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| Zdroj: | Molecular and Cellular Biology; May 1986, Vol. 6 Issue: 5 p1838-1842, 5p |
| Abstrakt: | The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions. |
| Databáze: | Supplemental Index |
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