| Autor: |
Langer-Safer, P R, Lehrman, S R, Skalka, A M |
| Zdroj: |
Molecular and Cellular Biology; October 1985, Vol. 5 Issue: 10 p2847-2850, 4p |
| Abstrakt: |
Murine 3T3L1 preadipocytes transformed by avian sarcoma virus were unable to differentiate in response to insulin or dexamethasone plus 1-methyl-3-isobutylxanthine, both potent inducers of differentiation of the nontransformed 3T3L1 parental line. Conditioned medium from transformed cells contained a relatively heat-stable factor(s) which inhibited the differentiation of untransformed parental 3T3L1 cells but did not induce any changes in their morphology. A protease-sensitive mitogen was also detected in the medium. The relationship between the two activities remains to be elucidated. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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