| Autor: |
Albuquerque, C. F., Silva, S. H. Marques da, Camargo, Z. P. |
| Zdroj: |
Journal of Clinical Microbiology; April 2005, Vol. 43 Issue: 4 p1944-1946, 3p |
| Abstrakt: |
ABSTRACTIn an attempt to improve the specificity of an enzyme-linked immunosorbent assay (ELISA) for the diagnosis of paracoccidioidomycosis (PCM), sera from patients with PCM were tested using various approaches, such as sodium metaperiodate antigen (gp43) treatment, a serum absorption process with Candida albicansor Histoplasma capsulatumantigens, and dilution of serum in galactose, the main common epitope among pathogenic fungi. The maximum specificity found in this ELISA was 84%. All of these procedures proved inefficient for eliminating all cross-reacting antibodies and obtaining an ELISA specific for PCM diagnosis. |
| Databáze: |
Supplemental Index |
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