Hepatitis C Virus Isolates from Argentina Disclose a Novel Genotype 1-Associated Restriction Pattern

Autor: Gismondi, Mari´a Ine´s, Staendner, Lothar Heinrich, Grinstein, Sau´l, Guzma´n, Carlos Alberto, Preciado, Mari´a Victoria
Zdroj: Journal of Clinical Microbiology; March 2004, Vol. 42 Issue: 3 p1298-1301, 4p
Abstrakt: ABSTRACTHepatitis C virus isolates which disclosed a novel genotype 1-associated restriction pattern by restriction fragment length polymorphism analysis were characterized. Except for a mother and child pair, the patients were unrelated. Sequence analysis showed a G?A substitution leading to a new RsaI recognition site. Phylogenetic analysis revealed that these isolates constitute a novel genetic lineage within the main cluster of genotype 1 strains.
Databáze: Supplemental Index