| Autor: |
Hamilton, Marilyn S., Abel, David M., Ballam, Yolanda J., Otto, Mary K., Nickell, Angela F., Pence, Lisa M., Appleman, James R., Shimasaki, Craig D., Achyuthan, Komandoor E. |
| Zdroj: |
Journal of Clinical Microbiology; July 2002, Vol. 40 Issue: 7 p2331-2334, 4p |
| Abstrakt: |
ABSTRACTExploiting the high sensitivity of the chemiluminescence phenomenon, an accurate and sensitive point-of-care test, called the ZstatFlu-II test (ZymeTx, Inc., Oklahoma City, Okla.), was developed to detect influenza virus infections. The ZstatFlu-II test takes 20 min and requires approximately 2 min of “hands-on” time for operational steps. The ZstatFlu-II test does not distinguish between infections with influenza virus types A and B. ZstatFlu-II test results are printed on Polaroid High-Speed Detector Film, allowing test results to be archived. A prototype version of the ZstatFlu-II test was evaluated during the 2000-to-2001 flu season with 300 nasal aspirate specimens from children at a pediatric hospital. Compared to culture, the ZstatFlu-II test had 88% sensitivity and 92% specificity. The Directigen test had a sensitivity of 75% and a specificity of 93%. The sensitivity of the ZstatFlu-II test was significantly higher than that of the Directigen test (P< 0.0574). |
| Databáze: |
Supplemental Index |
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