A human immunodeficiency virus type 1 (HIV-1)-based retroviral vector system utilizing stable HIV-1 packaging cell lines

Autor: Carroll, R, Lin, J T, Dacquel, E J, Mosca, J D, Burke, D S, St Louis, D C
Zdroj: The Journal of Virology; September 1994, Vol. 68 Issue: 9 p6047-6051, 5p
Abstrakt: We have constructed stable human immunodeficiency virus (HIV) packaging cell lines that when transfected with an HIV-based retroviral vector produce packaged vectors capable of transducing susceptible CD4+ cells. This HIV-1-based retroviral vector system has the potential for providing targeted delivery and regulated expression of immunogens or antiviral agents in CD4+ cells.
Databáze: Supplemental Index