| Autor: |
Prévost-Blondel, A, Chassin, D, Zeliszewski, D, Dorval, I, Sterkers, G, Pannetier, C, Guillet, J G |
| Zdroj: |
The Journal of Virology; December 1995, Vol. 69 Issue: 12 p8046-8050, 5p |
| Abstrakt: |
Human helper T-cell (Th) responses to influenza A virus were studied by analyzing T-cell receptor V beta gene diversity in hemagglutinin-specific Th lymphocytes. The T-lymphocyte population from peripheral blood became quickly oligoclonal when stimulated in vitro with the HA306-329 peptide, and T-cell receptor V beta 3 genes were mainly expanded. Moreover, specific junctional region oligonucleotide probes corresponding to hemagglutinin-specific clones were used to estimate temporal diversity during antigenic stimulations. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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