Autor: |
Gowda, S D, Stein, B S, Steimer, K S, Engleman, E G |
Zdroj: |
The Journal of Virology; March 1989, Vol. 63 Issue: 3 p1451-1454, 4p |
Abstrakt: |
Human cells infected with a recombinant vaccinia virus containing human immunodeficiency virus type 1 gag-pol genes produced large amounts of human immunodeficiency virus gag proteins beginning at 1 h and peaking at 48 h postinfection. We show that these polyproteins are processed accurately into mature forms and that the viral polymerase gene is encoded as a 160-kilodalton gag-pol fusion protein, most likely by translational frameshifting from the gag into the pol reading frame. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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