Restriction analysis and homology studies of the bovine adenovirus 7 genome

Autor: Hu, S L, Battles, J K, Potts, D E
Zdroj: The Journal of Virology; September 1984, Vol. 51 Issue: 3 p880-883, 4p
Abstrakt: We located the cleavage sites for restriction endonucleases EcoRI, HindIII, and BamHI on the genome of bovine adenovirus 7. Cross-hybridization at reduced stringency revealed two regions of homology shared by the DNA of human adenovirus 2 and bovine adenoviruses 7 and 3. These regions correspond to the hexon and the IVa2 protein genes of the human adenovirus. Another region of homology shared only by the human adenovirus and bovine adenovirus 7 corresponded to the penton or the polypeptide IIIa genes. These results allowed us to align the restriction map of bovine adenovirus 7 with respect to the other adenoviruses.
Databáze: Supplemental Index